How they really differ
Descript is an editor first: you decide what stays and it makes the edit easy. OpusClip is a selector first: it decides which moments might work as clips, and you review them.
Descript can also make clips, but you pick the moments yourself. OpusClip saves that hunting time but its picks still need a human check before posting.
Using both
Edit and publish the full episode in Descript, then run the finished video through OpusClip to pull a batch of short clips for social.
The verdict
Descript for editing the main video, OpusClip for repurposing it. Solo creators short on time often start with OpusClip; anyone editing raw recordings needs an editor like Descript.
Want the full write-up on each? Read our Descript review and OpusClip review.